Proceedings of the 5th International Congress on Coronary Artery Disease

Florence, Italy, October 19-22, 2003




Basil S. Lewis
Director, Department of Cardiovascular Medicine
Lady Davis Carmel Medical Center
Louis Edelstein Professor of Medicine and Medical Research
Bruce Rappaport School of Medicine
Technion-Israel Institute of Technology
Haifa, Israel

David A. Halon
Deputy Director, Department of Cardiovascular Medicine
Lady Davis Carmel Medical Center
Clinical Associate Professor
Bruce Rappaport School of Medicine
Technion-Israel Institute of Technology
Haifa, Israel

Moshe Y. Flugelman
Deputy Director, Department of Cardiovascular Medicine
Lady Davis Carmel Medical Center
Senior Lecturer
Bruce Rappaport School of Medicine
Technion-Israel Institute of Technology
Haifa, Israel

Gian Franco Gensini
Director, General Medicine and Cardiology Clinic
Careggi Hospital
Professor of Medicine and Cardiology
Dean, Faculty of Medicine
Florence Medical School, University of Florence
Florence, Italy



The last few years have witnessed major advances in the battle against cardiovascular disease, the major killer of our time.

This book presents chapters based on material presented at ICCAD5 the 5th International Congress on Coronary Artery Disease, Florence, Italy, on October 19-22, 2003. With the literal explosion of data in the field, it is difficult to keep abreast of new information. We hope that this volume will assist in this regard, and help us develop better strategies for patient management and new directions for research.

We thank most sincerely the Congress faculty and participants who submitted chapters to this publication. Our thanks are also due to the pharmaceutical and manufacturing industry, whose generous support made the Congress possible, to Kenes International Congress Organizers and to our dedicated staff, colleagues, friends and families for their help, support and advice in planning and arranging the meeting.

Florence, October 2003

Basil S. Lewis
David A. Halon
Moshe Y. Flugelman
Gian F. Gensini




Basic Research, Molecular Biology

Macrophage Foam Cell Formation without LDL Modification (Invited Lecture)
H.S. Kruth, W. Huang, I. Ishii, W.-Y. Zhang and Bin Zhao

Immunotherapy of Atherosclerosis (Invited Lecture)
P.K. Shah and Kuang-Yuh Chyu

Interleukin-10 and Lipid Peroxidation After Primary Angioplasty
A. Dominguez-Rodriguez, P. Abreu-Gonzalez, J. Ferrer, M. Vargas, A. de la Rosa and M. Garcia-Gonzalez

Cardiac Shock Wave Therapy Works Via Autoangiogenesis and Increases Perfusion and Exercise Tolerance in Endstage CAD Patients
A. Gutersohn, E. Marlinghaus and R. Erbel

Paraoxonase L55M Polymorphism and Coronary Artery Disease in Farmers A Preliminary Report
J. Koochmeshgi, S.M. Hosseini-Mazinani, N. Hoseinpur, S. Zare-Karizi, M.J. Hashemi, H. Azarnik and F. Soheilifar

Induced Hyperhomocysteinemia and Thrombin Generation in Patients with Coronary Artery Disease
T.B. Domagaa, A. Undas, J. Dropiski, M. Celinska-Lwenhoff, M. Rybak-Krzyszkowska, T. Lwenhoff and A. Szczeklik

Fluid Shear Stress, Blood Coagulation and Epigenetic Topography of Lymphocytes at Atherosclerosis: Changes of Gene Expression?
A.I. Teplyakov

Exogenius PDGF-AB in Vitro Induce Apoptotic Changes of Epigenomic Topography of Lymphocytes Chromatin in Patients with CHD?
A.I. Teplyakov

A Novel Ultrapotent Poly (ADP-ribose) Polymerase Inhibitor Improves Cardiac and Endothelial Dysfunction in Rat Model of Chronic Heart Failure
P. Pacher, L. Liaudet, J.G. Mabley and C. Szab


Pathology, Pathophysiology

Chronic Inhibition of NO Synthesis in Itself Promotes Structural Intimal Remodeling of the Rat Aorta (Invited Lecture)
M.A. Rossi


Infection, Inflammation, Inflammatory Markers

Antibiotics and Vaccines Against Atherosclerosis: What Wasnt Said (Invited Lecture)
E. Gurfinkel

Studies Examining Effect of Antibiotics on Human Atherosclerotic Lesions (Invited Lecture)
A. Shor

Acute and Chronic Effects of Cocaine on Inflammatory and Immune Responses
A. Siegel, J. Mendelson, M. Sholar, N. Mello, J. Halpern, M. Kaufman, P. Renshaw, S. Lukas, G. Tofler, K. Lewandrowski, J. Glowacki and P. Ridker

C-reactive Protein, Inflammation and Lipids as Risk Factors for Coronary Artery Disease and Myocardial Infarction
I. Burazor, M. Burazor, D. Dimic and N. Burazor

The Relationship of Selected Fibrinolytic Markers to Early Atherosclerosis
M. Hutyra, L. Slavik, D. Novotny, J. Lukes, D. Karasek,  M. Halenka and H. Vaverkova

Acute Myocardial Infarction and Bilateral Aseptic Femoral Necrosis in a Young Patient with Mixed Hyperlipoproteinemia
D. Eleftheriadis, P. Vrizidis and N. Eleftheriadis


Lipids, Lipoproteins, Atherosclerosis

The Postmenopausal Hormone Replacement Therapy Alters Lipoprotein Composition Leading to an Overestimation of its Low-Density Lipoprotein Cholesterol Lowering Effect
J.L. Vieira, E.H. Moriguchi, M.E. Gomes and A.B. Almeida

Genetic Polymorphisms in Patients with Premature Coronary Artery Disease
A. erne, B. Peterlin, I. Kranjec and M. erek

Polymorphism 174G/C IL6 and Acute Coronary Syndrome
M. Cercek, I. Kranjec, B. Peterlin and A. Cerne

The Contribution of Serum Ferritin to Coronary Heart Disease
V. Karagkiozaki, I. Litsas, L. Mporgi, S. Terzi, M. Passalidou, V. Kesidis, J. Stamatopoulou, A. Karali, L. Gerontidis and O. Koutsogiannis

Coronary Artery Disease in African and Caucasian South Africans
R. Nethononda, M. Essop, A. Mbewu and J. Galpin

Lifestyle in Teens-Predictor Factors for Cardiovascular Disease
E. Boeriu, S. Mancas, G. Doros, M. Gafencu, M. Marc,  C. Vernic and M. Serban

Additive Effects of Simvastatin and Ramipril on Inflammatory Cytokines Interferon-g, Tumor Necrosis Factor-a, Interleukin-6 and C-Reactive Protein in Diabetic Patients with Hyperlipidemia and Coronary Artery Disease
L. Tan, S. Tan, L. Berk and L. Lukman

The Effect of Non-pharmacological Treatment on Cardiovascular Risk Factors
R. Santos, J. Freitas, A. Monteiro, I. Rebelo and M. Macedo

In Vitro Photodynamic Diagnosis of Coronary Artery Atherosclerosis
D. Biay, A. Derkacz, M. Wawrzyska, M. Kwany, A. Bednarkiewicz and W. Strk


Epidemiology, Prevention, Risk Factors

International Trends in Stroke Mortality (Invited Lecture)
C. Sarti

Cardiovascular Risk Factors and Therapeutical Approach in Hypertensive Menopausal Women
V. Karagkiozaki, I. Litsas, L. Mporgi, M. Passalidou, V. Kiourtsidou, P. Kesidis, E. Kalaitzidou, A. Karali and O. Koutsogiannis

Antiphospholipid Antibodies and Hormone Related Thrombosis
A.M. Conti-Kelly, T. Greco and T.P. Greco

Smoking Habit at Younger Patients with Acute Myocardial Infarction
D. Glavas, I. Vukovic, D. Duplancic, M. Vujicic, D. Fabijanic, L. Giunio, D. Miric, P. Lozo and R. Ermacora

Antiphospholipid Antibodies (APL) in Women with Premature Coronary Artery Disease
T. Greco, A.M. Conti-Kelly and T.P. Greco

Heart Prevention in Immigrant Turkish Women Smoking Cessation
M. Hochleitner

Serum Homocysteine Levels and C667T MTHFR Gene Polymorphism in Patients with Type 2 Diabetes
B. Idzior Walu, M. Sanak, M. Walu, K. Sztefko, P. Miarka and J. Sieradzki

Hypoestrogenemia of Hypothalamic Origin is Associated with Coronary Artery Disease in Premenopausal Women. The WISE Study
C.N. Bairey Merz, B.D. Johnson, B.L. Sharaf, V. Bittner, S.L. Berga, G.D. Braunstein, T.K. Hodgson, K.A. Matthews, C.J. Pepine, S.E. Reis, N. Reichek, W.J. Rogers, G.M. Pohost and S.F. Kelsey

Hostility Is a Risk Identifier But Not a Primary Cause for Premature Coronary Heart Disease
D. McGill

A Positive Relationship Between Hostility Levels and Increased Platelet Reactivity in Young Males with CHD
D. McGill

Dietary Habits and Psychosocial Factors as a Risk For Development of Coronary Heart Disease in Bulgarian Women
Y.T. Yotov and V.N. Sirakova

Early Predictors of Atherosclerosis in Healthy 50-year-old Volunteers
W. Ruminski, H. Klepacka, M. Skorski, A. Mirek and T. Klecha

Secondary Risk Factors in the Progression of Coronary Artery Disease
V. Rudzite, E. Jurika, D. Fuchs, U. Kalnins, A. Erglis and K. Trusinskis

Clinical Relationships Between the Antiphospholipid Antibody Syndrome and Coronary Artery Disease
N.N. Chapaeva, A.A. Demin and A.M. Dmitriev


Angina Pectoris

Angina Treatment Patterns Survey. Current Status of the Diagnosis and Management of Patients with Stable Angina Pectoris in the Czech Republic (Invited Lecture)
J. Hradec, V. Chaloupka and M. Sachov

Functional Status Improvement After Enhanced External Counterpulsation (EECP) for Treatment of Chronic Angina Pectoris
E.D. Kennard, G. Linnemeier and S.F. Kelsey

Beneficial Effect of Short-time Physical Rehabilitation on the Autonomic System Activity in Patients with Coronary Artery Disease (CAD)
A. Furgaa, W. Kolasiska-Kloch, M. Dendura, . Dobrek, G. Krlczyk and P.J. Thor


Unstable Angina, Acute Coronary Syndromes

How Early Can We Diagnostic Acute Coronary (Invited Lecture)
Osama Abdel Aziz

Acute Coronary Syndrome and Low Molecular Weight Heparin, Glycoprotein IIb/IIIa Receptor Antagonists, Clopidogrel, Urgent Revascularization: Selective Use or Polytherapy for All Patients (Invited Lecture)
U. Thadani

Troponin T in Patients with Unstable Angina Can Predict Future Events and Angiographic Findings
M. Burazor, I. Burazor, S. Stefanovic and A. Stankovic

Expression of CD14 Receptor and Chlamydia Pneumoniae Membrane Antigens in Coronary Atherosclerotic Lesions Grade V and VI Study on 46 Subjects
M. Radoi, I. Agache, M. Anghel, M. Penciu and F. Leasu

Predictive Value of Prior Statin Therapy on Acute Coronary Syndrome Presentation
B. Kilickiran Avci, St. Sahin, E. Duygu, S. Pehlivanoglu, Z. Ongen and VA. Vural

Management in Acute Coronary Syndrome with Severe Heart Failure: Supportive Treatment with Intraaortic Balloon Pump
Z. Mitrev, A. Vasileva, I. Milev, V. Belostotsky, S. Jovanovska and V. Ampova


Acute Myocardial Infarction

Reperfusion Management in Acute Myocardial Infarction (Invited Lecture)
H.-J. Rupprecht

Coronary Vascular Remodeling After Myocardial Infarction: Pharmacologic Modification (Invited Lecture)
B.I. Jugdutt

The Triage To Rescue Percutaneous Coronary Interventions in ST-elevation Acute Myocardial Infarction
E. Balli, L. Calugi, M. Taglioli, E. Pedemonte, A. Giomi, M. Chiti and F. Del Citerna

Primary Angioplasty in a Peripheral Hospital Equipped with Catheterization Laboratory: Transfer of an Experienced Operator from the Reference Centre
F. Meucci, F. Bonechi, M. Nieri, A. Del Rosso, P. Bartoli, M. Sansoni, A. Zipoli, C. Giglioli, M. Comeglio and M. Margheri

Direct Stenting in More Than One Third of All Primary PCI for STEMI
I. Bernat, J. Peek and P. Boek

Enoxaparin in Primary Angioplasty: In-Hospital and one Month Results of a Pilot Study
J. Lacunza, J.R. Gimeno, R. Lpez-Palop, E. Pinar, A. Garzn, R. Rubio, D. Saura, T. Agull-Ortuo, F. Prez-Lorente, F. Pic, J.A. Noguera and M. Valdes

The Value of ECG in the Prediction of Success of Thrombolysis in Patients with Acute Myocardial Infarction
I.A. Vogiatzis, T. Karamitsos, E. Kambitsi, D. Samanidis, V. Tsagaris, P. Prodromidis and I.M. Vogiatzis

Predictive Value of admission Glycemia in Patients with First Acute Myocardial Infarction
B. Pencic, M. Dekleva, V. Celic, N. Kosti, Z. Rasic, B. Putnikovic, A. Ignjatovic and M. Panic

The Prognosis Value of Admission Heart Rate on Mortality in Patients with Acute Myocardial Infarction Treated With Primary Angioplasty
A. Amaro, E. Paredes, F. Gude, C. Iglesias, R. Trillo, L. Martinez-Sande, P. Souto, A. Garca-Lpez and D. Lpez-Otero

Beneficial Effects of Amlodipine on Vascular and Ventricular Remodeling During Post-infarct Healing
B.I. Jugdutt, H. Idikio and V. Menon

Stroke After Acute Myocardial Infarction: Uncommon but Fatal Complication
M. Ivanusa and Z. Ivanusa

In-hospital Outcome in Octogenarians with Acute Myocardial Infarction Undergoing Primary Coronary Angioplasty
Kenji Ando, Soga Yoshimitsu, Kei Nishiyama, Shinichi Shirai, Koyu Sakai, Masashi Iwabuchi, Hiroyoshi Yokoi, Hideyuki Nosaka and Masakiyo Nobuyoshi

Compliance to Secondary Prevention Guidelines for Acute Myocardial Infarction in an Industrial Isolated Area in North Greece
D. Eleftheriadis, P. Vrizidis and N. Eleftheriadis

Myocardial Infarction in Women
T. Momcilov Popin, Dj. Stojsic, A. Stojsic Milosavljevic, D. Zivkov Saponja, A. Ilic, M. Potic and N. Radovanovic

Percutaneous Coronary Intervention for Acute Myocardial Infarction in the Elderly: Comparison on Clinical Outcome between Younger Patients, Septuagenarians Patients and Octogenarians Patients: Multicenter Registry in Japan
S. Nakamura, M. Hirose, E. Saito, T. Miyauchi, A. Kanazawa, K. Hozawa, H. Nakamura, K. Yamamoto, N. Makishima, S. Nakamura and J. Koyama


Arrhythmias, Electrophysiology

Analysis of Heart Rate Variability and Early Recurrence of Atrial Fibrillation After Electrical Cardioversion
R. Vaiciulyte and L. Losinskiene

Surgical Intervention for Chronic Atrial Fibrillation in Conjunction to Other Cardiac Diseases
V. Panagiotakopoulos, M. Argiriou, Ch. Charitos, E. Koletsis, P. Dedeilias and Ch. Lolas


Diagnostic Methods

Ultrasound and Coronary Heart Disease Prevention (Invited Lecture)
P.R. Liebson

Myocardial Contrast Echocardiography in Coronary Artery Disease (Invited Lecture)
Y. Almanaseer and J. Gardin

Noninvasive Strategy for Early Prediction of Transplant Coronary Arteriopathy and Timing of Coronary Angiographies in Heart Transplant Recipients
M. Dandel, F. Knollmann, E. Wellnhofer, H. Lehmkuhl, M. Hummel and R. Hetzer


Endothelial Function, Vascular Biology

Lack of Association between Chlamydia Pneumoniae Antibodies and Endothelial Function as Assessed by Flow-mediated Dilation
B.B. Malmqvist, B.R. Diness, K. Krogsgaard, L.H. Thomassen, G.B. Jensen and the IAMA Group

Improved Vein Graft Patency Using a Novel No-touch Technique Is Due to Preserved Nitric Oxide Synthase
M.R. Dashwood, R. Anand, A. Loesch, D. Filbey, M. Karlsson and D.S.R. Souza

Chronic Physical Exercise Prevents Age-related Decline in Antioxidant Status and Endothelium-dependent Vasodilation in Healthy Men
F. Franzoni, L. Ghiadoni, F. Galetta, V. Lubrano, A. Virdis, G. Salvetti, S. Taddei, G. Santoro and A. Salvetti

Endothelial Function and Carotid Artery Wall Characterization by Ultrasonic Integrated Backscatter in Elderly Athletes
F. Galetta, F. Franzoni, A. Virdis, L. Ghiadoni, G. Salvetti, S. Taddei, A. Salvetti and G. Santoro

Impaired Endothelial Function in Patients with Peripheral Arterial Disease Assessed by Pulse Wave Analysis
J. Kals, P. Kampus, P. Pder, A. Pulges, R. Teesalu and M. Zilmer

Endothelial Haemostatic Markers in Members of Families with Familial Combined Hyperlipidemia
D. Karsek, H. Vaverkov, M. Hutyra, D. Novotn, M. Budkov and L. Slavk

Hyperinsulinaemia and Postprandial Lipaemia in Cardiological Syndrome X
W. Kolasiska-Kloch, A. Jabrocka, W. Leniak, M. Kloch and A. Dembiska-Kie

ICAM-1 as a Marker of Endothelial Dysfunction in Patients with Coronary Heart Disease
R. Porba, A. Skoczyska, A. Derkacz, B. Turczyn and A. Wojakowska


Ventricular Function, Heart Failure

Which Ethical Principles to use in Heart Failure? (Invited Lecture)
H. Geschwind

Left Ventricular Diastolic Function Assessed Using Tissue Doppler Imaging in Elderly Athletes
F. Galetta, F. Franzoni, F.R. Femia, N. Roccella, F. Pentimone and G. Santoro

Can SSS (Summed Stress Score) Derived from MPI, Be an Accurate Indicator of Left Ventricular Function
M. Vavlukis, J. Maksimovic, V. Borozanov, Lj. Georgievska-Ismail, D. Pop-Gorceva, V. Majstorov, I. Peovska, L. Poposka, B. Taneva, N. Kostova and T. Trajcevski

Echocardiographic Diagnostic Markers for the Discrimination of Ischaemic from Dilated Cardiomyopathy
G. Papanagnou, G. Karatasakis, S. Kakouros, D.B. Panagiotakos, K. Filis, P.K. Toutouzas, C. Stefanadis and D.V. Cokkinos

The Use of N-terminal Pro Brain Natriuretic Peptide (NT-proBNP) in Assessment of Left Ventricular Dysfunction in Patients in Emergency Department
R. Pudil, J. Gregor, M. Tich, R. Praus and J. Mal

How to Treat Patients with Ischemic Heart Failure?
J. Roncalli

Pre-hospital Thrombolysis Reduces Incidence of Ischemic Heart Failure
J. Roncalli

Improvement of Haemodynamics by AT1-Antagonists-addition to ACE-inhibitor Pretreated Patients with Severe Chronic Heart Failure Based on Coronary Artery Disease
B. Gremmler, K. Kisters, M. Kunert, H. Schleiting and L.J. Ulbricht

Combined Effects of Ramipril and Carvedilol on Attenuating Interferon-g, Tumor Necrosis Factor-a, Interleukin-6 and C-Reactive Protein, and Improving Heart Failure in Diabetic Patients
S. Tan, L. Tan, L. Berk and L. Lukman


Neurohormonal Aspects

The Course of NT-proBNP Values in Elective vs. Primary PTCA
B. Gremmler, M. Kunert, H. Schleiting, B. Enxing, K. Kisters and L.J. Ulbricht

NT-proBNP Values in Correlation to Re-occlusion Rate After PTCA
B. Gremmler, M. Kunert, H. Schleiting, B. Enxing, K. Kisters and L.J. Ulbricht

Triiodothyronine Concentration and Left Ventricular Function Assessment: A Combined Bioumoral and Functional Strategy for the Risk Stratification of Patients with Heart Failure
A. Pingitore, A. Ripoli, S. Turchi, A. Bottoni, MC. Taddei, P. Landi, A.B. Favilli, M. Raciti, A. LAbbate and G. Iervasi

Mental Stress-induced Platelet Activation and Increases in C-reactive Protein Concentration in Coronary Artery Disease
A. Steptoe, P. Strike, K. Magid, L. Brydon, S. Edwards, J. Erusalimsky and J. McEwan

Elevated N-terminal Pro-Brain Natriuretic Peptide (NT-proBNP) in Acute Myocardial Infarction Following Primary Angioplasty Is Associated with Poor Short-term Prognosis
R. Witthaut, D. Stoevesandt, R. Prondzinsky, I. Stabenow and K. Werdan


Myocardial Viability, Stunning

ARBs Limit Myocardial Stunning and Upregulate AT2 Receptors During Reperfused Myocardial Infarction
B.I. Jugdutt and V. Menon

The Effects of Partial Fat Acid Inhibitor Trimetazidine on Global and Regional Diastolic Left Ventricle Function in Patients with Hibernating Myocardium
A. Kastanajan, N. Nelassov, N. Drobotia, O. Eroshenko and N. Kazarian

Viable Myocardium: Blood Antioxidative Defense and Content of the Erythrocyte Intracellular Calcium
S. Komissarova, N. Moroz-Vadalajskaya, N. Kozlova, D. Kostin and E. Slobozhanina

Conduction Cell Necrosis Due to Cardioplegic Arrest
F. Sayk, S. Krger, J.F.M. Bechtel, H.H. Sievers and C. Bartels


Systemic Hypertension

Serum Uric Acid Is Related to Metabolic Disturbance and Associated to Serum Aldosterone in Essential Hypertension
M. Kasner, B. Jelakovic, M. Laganovic, T. Zeljkovic, D. Kuzmanic, G. Borso, T. Smuc, D. Gamberger and P. Roncevic

Low Birth Weight Does Not Influence Blood Pressure Through Reduced Kidney Volume
M. Laganovi, B. Jelakovi, D. Kuzmani, G. Boro, T. Ronevi, M. Vdovi, T. Zeljkovi, M. Kaner, T. muc and D. Gambergerr

Pulse Pressure as Determinant of Endothelial Dysfunction in Never Treated Hypertensive Patients
A. Sciacqua, R. Maio, R. Ceravolo, S. Cassano, M. Vatrano and F. Perticone

The Metabolic Syndrome in Hypertensive Patients with Left Ventricular Hypertrophy After 5 Years
I.S. Tasi, B. Lovi, V. Stefanovi, D. orevi, S. Ili, T. Savi, N. Miladinovi Tasi, M. Deljanin Ili and G. Stojkovi

Blood Pressure Response to Exercise Contributes to Cardiovascular System Evaluation
C. Graidis, N. Hamouratidis, D. Dimitriadis, I. Vogiatzis, M. Polizois, E. Kambitsi and P. Gianakopoulou



Angina Prevention by Heart Rate Slowing: If Current Blockade with Ivabradine (Invited Lecture)
J. Borer

Increase of Cardiac Events in Continuous Long-term Dosing with Nitrates (Invited Lecture)
K. Kanamasa

Attenuation of Myocardial Stunning by Angiotensin II Type 1 Receptor Blockade with Candesartan: Role of the Type 2 Receptor
B.I. Jugdutt and V. Menon

Beta-blockers Attenuate Hypolipidemic Effect of Statins in Patients with Diabetes Mellitus Type 2 in Secondary Prevention
J. Lietava, V. Kosmlov and R. idlo

Predictors of the Hypotensive Effect of Betaxolol in Patients with Coronary Artery Disease and Hypertension
B. Gryglewska and T. Grodzicki

Platelet Glycoprotein IIIa Polymorphism and Complementary Antithrombotic Actions of Aspirin and Clopidogrel in Coronary Artery Disease
J. Dropiski, M. Sanak, W. Wgrzyn, A. Cmiel, A. Dyszkiewicz-Korpanty, B. Brzezinska-Kolarz and A. Szczeklik

The Cardiac Safety of Propiverine-HCl (Mictonorm) Assessed in Healthy Female Subjects
L. Sydorchuk, N. Tsvitbaum, F. Donath, S. Biletsky and K.M. Eckl

Relationship Between Physical Exercise, Nitric Oxide and Endothelial Dysfunction in Older and Young People
F. Franzoni, F. Galetta, C. Morizzo, V. Lubrano, C. Palombo, G. Santoro, E. Ferrannini and A. Quiones-Galvan


Prognosis and Progression

Sudden Cardiac Death Due to Recreational Exercise in Physicians
Z. Durakovi, M. Miigoj-Durakovi, N. orovi and J. kavi

Brain Natriuretic Peptide as a Predictor of Future Recurrence of Angina Pectoris
H. Takase, A. Takahashi, T. Toriyama, T. Sugiura, R. Ueda and Y. Dohi

Elevated Level of Anti-phospholipid Antibodies and Increased Carotid-artery Intima Media Thickness as an Early Sign of Atherosclerosis in Patients with Systemic Autoimmune Diseases
J. Dropinski, W. Szczeklik, W. Wgrzyn and B. Domagala


Computer Applications

Multi-dimensional Visualization of Coronary Aberrancies Using Multi Detector Computed Tomography
P. van Ooijen, J. Dorgelo, W. Tukker, H. Willemsen and M. Oudkerk

Computerized Mapping of ECG and ST Segment: Isolation and Introduction of the Seventh Wave
V.R. Abbasi

Virtual Coronary Angioscopy EBCT vs MDCT
P. van Ooijen, J. Dorgelo and M. Oudkerk


Coronary Flow and Physiology

Coronary Arterial Remodelling at Bifurcation Points
P. Teefy, P. Chang, A. Borys, D. Massel, K. Sridhar and D. Almond

A Comprehensive Investigation of Coronary Artery Disease in Hypertensive Patients with Advanced Left Ventricular Dysfunction
C. de C Frimm, V.F.A. Pereira, A.C.T. Rodrigues, J.M. Tsutsui and M. Cri


Interventional Cardiology

Invasive Procedures in an Out-patient Setting. Aspects of the Stable-Angina-Pectoris Registry (Star) (Invited Lecture)
K. Kleinertz

Outcomes of Medical and Interventional Therapy in Elderly Patients with Acute Coronary Syndromes (Invited Lecture)
D.A. Halon, I. Dobrecky-Mery, S. Adawi and B.S. Lewis

Stenting in Multi-Vessel Disease. Angiographic Outcome in the GABI II Study and Comparison with Results of the GABI I Trial
U. Dietz, H.-J. Rupprecht, J. vom Dahl and C. Hamm

Transradial Coronary Intervention for Chronic Total Occlusion
T. Shiono, S. Saito, S. Tanaka, Y. Miyashita, S. Takahashi, F. Arai and H. Domae

Intervention of Chronic Total Occlusion Via Radial Artery
C.-W. Goh

Distal Pressure Measurement beyond Total Coronary Occlusions in Patients Presenting with an Acute Coronary Syndrome: Collateral Flow Index and Correlation with Angiographic Collateral Grade
S. Meisel, M. Shochat, S. Dacca, A. Shotan, B. Pelled, J. Shani and A. Frimerman

The Extent of Debulking in Directional Coronary Atherectomy in Relation to Occur Restenosis
A. Fukuda, M. Kitayama, H. Akao, H. Okazaki, K. Uesugi, T. Kasuga, M. Asano, S. Okubo, S. Kanemitsu and N. Takekoshi

Influence of Diabetes Mellitus in Patients with Long Coronary Lesions Undergoing Percutaneous Coronary Interventions: Multicenter PCI Registry in Japan
E. Saito, M. Hirose, T. Miyauchi, A. Kanazawa, S. Nakamura, K. Hozawa, H. Nakamura, K. Yamamoto, N. Makishima, S. Nakamura and J. Koyama

Contrast-induced Renal Impairment After Coronary Angiography: Risk-factors and Predictors
A. Wacker, W. Huber, J. Preiss, M. Hennig, A. Umgelter, A. Schoemig, U. Heemann and R.M. Schmid

Postinterventional Inhibition of Inflammatory Mediators After Clopidogrel
S. Zumhagen, E. Schulze-Bahr, R. Gradaus and B. Brisse

Fractional Intraarterial Admistration of Norepinephrine Save and Effective Treatment of Hypotension During Left Heart Catheterisation
J. Pesek, I. Bernat and P. Bocek

Percutaneous Coronary Intervention in the Elderly: Comparison on Clinical Outcome between Younger Patients, Septuagenarians and Octogenarians: Multicenter Registry in Japan
S. Nakamura, M. Hirose, E. Saito, T. Miyauchi, A. Kanazawa, K. Hozawa, H. Nakamura, K. Yamamoto, N. Makishima, S. Nakamura and J. Koyama


Interventional Devices

FX MiniRAIL Provides Long-term Reduction in Target Lesion Revascularization of De Novo and In-stent Lesions
T. Ischinger, R. Solar and E. Hitzke

The Impact of Rotablator in Patients with Chronic Hemodialysis
Saeko Takahashi, Shigeru Saito, Shinji Tanaka, Yusuke Miyashita, Takaaki Shiono, Fumio Arai, Hiroshi Domae and Shutaro Satake

Guiding Catheter Aspiration Technique That Has Both Advantages of Distal Protection and Down Sizing
T. Tsuchiya, M. Namura, M. Ikeda, T. Araki, N. Yoshida and A. Izawa

Preliminary results of the Arthos-Inert Coronary Stent Registry
C. Schukro, M. Derntl, S. Denk, B. Syeda, C. Strehblow, W. Sperker, M. Gyngysi and D. Glogar

Treatment of Long Coronary Lesions with Stenting, Cutting Balloon and Rotational Atherectomy, Immediate and Long-term Results: Multicenter Registry in Japan
S. Nakamura, J. Koyama, S. Nakamura, M. Hirose, E. Saito, T. Miyauchi, A. Kanazawa, K. Hozawa, H. Nakamura, K. Yamamoto and N. Makishima

Intracoronary Laser Photoremodeling (LP). The New Method in Restenosis Prevention After Percutaneous Coronary Intervention (PCI)
A. Derkacz, D. Bialy, M. Protasiewicz, K. Abramski, E. Pawlik, J. Arkowski and H. Nowosad

Utilization of Low-profile Intra-aortic Balloon Catheters Inserted by the Sheathless Technique in Acute Cardiac Patients: High Efficacy with a Low Complication Rate
S. Meisel, M. Shochat, S. Abu Sheikha, A. Osipov, A. Kogan, N. Anabussi, B. Suari, A. Frimerman, A. Shotan, G. Sahar and B. Peled


Drug Eluting Stents, Radiation

The Sirolimus Drug-eluting Stent: Experience from Greece (Invited Lecture)
V. Voudris and D.V. Cokkinos

Inhibition of C-Reactive Protein After Implantation of a Sirolimus-Eluting Stent
J.-L. Bueb, E. Tschirhart, G. Gilson, J. Beissel, M. Vaillant, P. Autier and D.R. Wagner

Stent-based Cytochalasin D Delivery Reduces Intimal Hyperplasia in a Porcine Coronary Model
K. Salu, J. Bosmans, Y. Huang, M. Hendriks, M. Verhoeven, A. Levels, X. Liu, I. De Scheerder, H. Bult and C. Vrints

Lumen Centering Versus IVUS-Probe Centering of Gamma Sources: Retrospective Evaluation of Doses to Intima and Adventitia for Intravascular Brachytherapy Cases
S. Chiu-Tsao, C. Zhang, A. Mahadevan, N. Patel, A. Maehara, N. Weissman, A. Bui, G. Mintz, M. Leon, B. Kluck, P. Teirstein, R. Waksman, H. Xie and L. Harrison


Cardiac Surgery

Changing Pattern of Coronary Artery Bypass Graft Surgery (Invited Lecture)
N. Hanayama, D. Abramov, B. Goldman, N. Desai, V. Guru, G. Christakis, M. Pelletier, G. Cohen, J. Sever and S. Fremes

Ischemic Mitral Regurgitation (Invited Lecture)
A. Trento

The Left Ventricular Wall After infarction: Assessment with Magnetic Resonance and Possibilities of Surgical Enhancement (Invited Lecture)
V. Dor, M. Di Donato, M. Sabatier and F. Civaia

New Surgical Approaches for Total Arterial Revascularization: Postoperative Non-invasive Evaluation of Arterial Cunduits (Invited Lecture)
J. Gurevitch, B. Orlov, T. Safadi, A. Zlotnic, V. Rubchevski, D. Dvir and D. Aravot

Transmyocardial CO2 Laser Revascularization (TMR) in Patients with "End Stage" Coronary Heart Disease Early and Midterm Results (Invited Lecture)
P. Hendzel, M. liwiski, Z. Juraszyski, A. Teresiska, M. Szymaska and K. Duda

Screening for Cerebrovascular Risk in Patients Undergoing Coronary and Carotid Surgery (Invited Lecture)
S. Castellani, M. Bagnoli, E. Tesi, D. Gecchele, C. Mazzanti and I. Carobbi

Avoiding Cognitive Damage After Cardiac Surgery The Challenge for the Future (Invited Lecture)
J. Kilo, M. Grimm, D. Zimpfer and E. Wolner

Coronary Revascularization with or without Extracorporeal Circulation
A. Molnar, T. Scridon and M. Barsan

Four Years Experience of Thoracic Aortic Disease with Stent-graft
A.S. Bortone, D. DAgostino, E. De Cillis and L. de Luca Tupputi Schinosa

Minimal Extracorporeal Circulation (MECC): Influence on Postoperative Bleeding of the Operative Technique for Coronary Artery Bypass Graft (CABG)
A. Fumero, C. Carro, S. Mermond, LF. Camilleri, S. David, P. Bailly and Ch. De Riberolles

Total Arterial Myocardial Revascularization with Right Gastroepiploic Artery and Bilateral Internal Thoracic Artery. An Analysis of Nine Years Experience
P. Greco, F. Formica, O. Ferro, L. Colagrande, A. Martino, F. Corti and G. Paolini

Coronary Artery Disease in Patients Awaiting Peripheral Arterial Reconstruction
J. Kramar, P. Sebesta, P. Sedivy, P. Formanek, P. Kmonicek, P. Biebl, E. Zdrahalova, J. Soupal, B. Jurenka and M. Stern

Off Pump Coronary Artery Bypass Grafting: Surgical Outcome in High- Risk Patients
A. Maizza, E. Tappainer, N. Pederzolli, A. Nocchi, V. Fiorani1 M. Romano, C. Lettieri, A. Stuani, M. Giovannini, R. Paladini, R. Zanini and M. Zogno

Strategy for Coronary Artery Bypass Grafting with Xenon CT Scanning In Patients with Cerebrovascular Disease
M. Nakao, K. Kondou, Y. Sawada, K. Asada, S. Mieno, A. Shimada, T. Tokumaru, K. Nakahara, M. Yoshida, Y. Nakai and T. Morimoto

Severity of Diabetic Retinopathy and Coronary-Artery-Bypass Surgery
T. Ono

Heamodynamic Changes During Off-pump Coronary Artery Surgery
V. Panagiotakopoulos, E.N. Koletsis, P.G Dedeilias, Ch. Charitos, M. Argiriou, J.N. Kokotsakis, E. Apostolakis and C.N. Romana

Coronary Artery Bypass Grafting in Patients with Dialysis-depending Renal Insufficiency
J.M. Knoerig, S. Saenger, Y. Finkbeiner, Y. Tzanavaros and A. Smechowski

Advantage of Simultaneous Coronary Artery Bypass and Left Ventricular Repair with Chronic Ischemic Heart Failure
Y. Takahara, S. Takeuchi, K. Mogi and M. Sakurai

In-situ Internal-thoracic-artery Grafting for a Patient with Medically Intractable Coronary Spasm and Angiographically Normal Coronary Arteries
T. Ono, T. Ohashi and T. Asakura

Hemodynamics After Hemofiltration During Extra-corporeal Circulation in Adults
T. Tirilomis, M. Friedrich, H. Srbu, I. Aleksic and T. Busch

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